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11 30th March 23:10
mercy
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Posts: 1
Default Methotrexate Update & Other News (insulin)


Maggie, MTX should not be taken with Vit. C or folic acid.... so don't drink
orange juice with your MTX and skip the folic acid until the following day.
Good luck.

Nettie


Hi Nina!

I keep meaning to ask you about the dose you're on. They told me that I
can't take the pills if I'm on more than 17.5mg. Has anyone ever told
you this? I wonder if there are different types of MTX or something?

Actually, I'm not going to be taking injections.....yet. I do have 20
insulin needles
at my disposal, however. For the last 3 weeks I have mixed the liquid
in juice & drank it. It hasn't bothered me thus far, but I am careful
to not eat high fat foods & gobs of protein in one sitting the day or so
before my dose as well as the couple of days following. This has made
all the difference. If I do get nauseated, I have the syringes ready &
I'm willing, but I promised I'd do the liquid for now. I was worried
that they'd make me come in for an injection class or something & I am
scared to go to the hospital with the flu running rampant through the
halls.
: ) I know how to do the injections, but when someone of authority
tells me no, then my head creates this fear of death & even
worse.....eating crow! :-

Hugs,
Maggie
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12 30th March 23:10
mercy
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Posts: 1
Default Methotrexate Update & Other News (abdomen)


Short needles are fine cuz you are only going into the upper layers of your
skin. Make sure you pull back on the plunger a tad first before pushing in
the MTX. You want to make sure you are not into a blood vessel. If you see
blood when you pull back, take it out and find a new place. I do them in my
thigh or sometimes my husband will give it to me in the fatty upper hip
area. Whatever works for you. I have never done it into my abdomen. Good
luck and write me if you need to.

Nettie
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13 31st March 06:10
nw
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Posts: 1
Default Methotrexate Update & Other News


"Mercy" <pickadillyNOSPAM@charter.net> skrev i meddelandet
news:vuf6kktoh09731@corp.supernews.com...


Nettie, are you sure about the vitamin C stuff? I've never heard or read that MTX
shouldn't be taken with that. RxList doesn't mention vitamin C either.
http://www.rxlist.com/cgi/generic/mtx_wcp.htm

Nina
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14 31st March 06:11
mercy
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Posts: 1
Default Methotrexate Update & Other News


I am getting this info from a fella who know a lot about nutrition, etc. He
said not to so I don't just to be on the safe side. It is not a big deal to
not take it IMO... just for that one day. Also, I have heard to never take
your meds with g****fruit juice. It can cause a bad tummy reaction.

Just passing along info that I have heard to you. Don't bet your buttie on
it though. But for me, I trust this person and do what he suggests. Hope
this helps you.

Nettie :>))
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15 31st March 06:11
jdwat
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Posts: 1
Default Methotrexate Update & Other News


Aww Flitter! I hope your wrong about the Vit C. The nurse told me to
take it with juice & that's what I've been doing. I haven't been taking
OJ, but most juice has a good amount, I think.

Speaking of....Did you know that g****fruit juice can cause certain meds
to become more potent in your system. They were studying it when I was
on Imuran. I'd say I read this about 1996 or '97 maybe. They warned
against taking immunosupressants in combo with g****fruit. Also blood
thinners & other serious meds. In fact they were hoping to come up with
a way to help people take less meds by supplementing it with g****fruit.
I have never heard another thing about it since, but I found it so
interesting at the time. They may have discovered they were wrong or
maybe the pharmaceutical company's sent the researches to Bermuda, via
the triangle. :-

Hugs4uBoth,
Maggie
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16 31st March 16:05
janers
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Posts: 1
Default Methotrexate Update & Other News (stomach)


Never take g****fruit juice with some HEART and or bp medications. It
effects the way the medication works.
It has nothing to do with stomach being upset or irritated it has to do
with the absorption of the drug. Ask your pharmacist about any heart or bp
med and IF the g****fruit juice will effect it.
Most will put it on the label, but some just do not. sad....
..
As far as Vitamin C? I have never heard it effecting mtx or any other drug
but HEY, what do I know. tee hee

Vitamin C right now is what everyone needs to up due to the flu season. It
was in the paper and also on some journals of medicine. It is suppose to
ward off the little bugs ya pick up.

janers
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17 31st March 16:05
j
External User
 
Posts: 1
Default Methotrexate Update & Other News (small intestine)


http://www.hc-sc.gc.ca/english/iyh/food/g****fruit.html Canadian Gov't
webpage

Consuming g****fruit or its juice (fresh or frozen) can increase, or less
commonly decrease, the effects of some drugs. There are several substances
in g****fruit that interfere with the way your body handles certain drugs.

These effects are known to be caused by the combination of g****fruit and
its juice with certain drugs and health products used in the treatment of
medical conditions, including, but not limited to:
<see list>

Sour oranges, such as Seville, or their juice, may have an effect similar to
g****fruit juice. Most other citrus fruits, such as lemons, limes, citrons,
naturally sweet oranges and tangerines are not thought to have this effect.
However, tangellos, a hybrid of g****fruit, may also interfere with drugs.

....
Canadian "Dartmouth Community Medical School"
<http://www.dartmouth.edu/dms/news/publications/dartmed/fall00/html/bench_to_bedside.shtml>

So far, the medications known to interact with g****fruit juice include
immunosuppressant drugs (such as cyclosporine); calcium channel blockers
(felodipine, amlodipine, verapamil, nifedipine, nisoldipine), which are used
to treat blood pressure or angina; many sedatives and anxiolytics
(midazolam, triazolam, alprazolam); certain hormones (estrogens and
corticosteroids); antihistamines (astemizole and terfenadine, the latter now
unavailable in the United States); certain antiseizure drugs
(carbamazepine); many of the statin drugs (atorvastatin, simvastatin,
lovastatin), which are used to lower blood lipids; and certain drugs used to
treat AIDS (the protease inhibitors ritonavir, saquinivir, and indinavir).
Other drugs are continually being added to this list.

As far as we know, no other fruits--such as apples, oranges, or cranberries
(or their juices)-- have the same effect that g****fruit does. The
g****fruit effect is probably due to certain of its chemical
components--6',7'-dihydroxybergamottin (a furanocoumarin) and/or naringin or
naringenin (both flavonoids)--which are thought to inhibit the CYP3A4 enzyme
in the small intestine.

We know we must make physicians and patients aware of how g****fruit juice
can affect many oral medications, but efforts to bring the issue to public
attention have had varied success around the world. Australia seems to be at
the forefront: pharmacists there are required by law to attach labels to
containers of cyclosporine, felodipine, midazolam, nifedipine, nisoldipine,
quinidine, terazosin, terfenadine, and triazolam stating: "Avoid eating
g****fruit and drinking g****fruit juice while being treated with this
medication." But other known g****fruit-drug interactions that could cause
considerable morbidity have not been so overtly flagged. And in the U.S.,
the warnings that appear in even the most recent edition (2000) of the
Physicians' Desk Reference are not comprehensive,


??
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18 31st March 16:05
jdwat
External User
 
Posts: 1
Default Methotrexate Update & Other News


Wow! So, they did finish the study. Thanks for that J! : )

Hope you have a Merry Christmas!

aHug4u,
Maggie
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19 31st March 16:05
mercy
External User
 
Posts: 1
Default Methotrexate Update & Other News


That is very interesting..... thanks for the feedback.

Nettie


Aww Flitter! I hope your wrong about the Vit C. The nurse told me to
take it with juice & that's what I've been doing. I haven't been taking
OJ, but most juice has a good amount, I think.

Speaking of....Did you know that g****fruit juice can cause certain meds
to become more potent in your system. They were studying it when I was
on Imuran. I'd say I read this about 1996 or '97 maybe. They warned
against taking immunosupressants in combo with g****fruit. Also blood
thinners & other serious meds. In fact they were hoping to come up with
a way to help people take less meds by supplementing it with g****fruit.
I have never heard another thing about it since, but I found it so
interesting at the time. They may have discovered they were wrong or
maybe the pharmaceutical company's sent the researches to Bermuda, via
the triangle. :-

Hugs4uBoth,
Maggie
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20 31st March 16:05
mercy
External User
 
Posts: 1
Default Methotrexate Update & Other News


I was told to just not take Vit C the day I take MTX.... the next day I can
continue. Also no folic acid the day I take MTX because it could hinder to
absorption or something of the MTX so I wouldn't get the full benefit.

Nettie
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